Starting XI with clubs
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| No | Name | Age | Club | Goal | Assist | Card | Sub. |
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| 1 | Fernando Muslera | 32 | Galatasaray |
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| 22 | Martín Cáceres | 31 | Lazio |
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| 19 | Sebastián Coates | 27 | Sporting CP |
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| 3 | Diego Godín | 32 | Atlético Madrid |
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| 17 | Diego Laxalt | 25 | Genoa |
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| 8 | Nahitan Nández | 22 | Boca Juniors |
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Out: 73' |
| 14 | Lucas Torreira | 22 | Sampdoria |
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| 15 | Matías Vecino | 26 | Internazionale |
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| 6 | Rodrigo Bentancur | 21 | Juventus |
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59'
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Out: 63' |
| 9 | Luis Suárez | 31 | Barcelona |
10'
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| 21 | Edinson Cavani | 31 | PSG |
90'
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Out: 90' |
| 10 | Giorgian De Arrascaeta | 24 | Cruzeiro |
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In: 63' |
| 7 | Cristian Rodríguez | 32 | Peñarol |
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In: 73' |
| 18 | Maximiliano Gómez | 21 | Celta de Vigo |
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In: 90' |
| Coach | Óscar Tabárez | 71 |
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