Starting XI with clubs
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| No | Name | Age | Club | Goal | Assist | Card | Sub. |
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| 1 | Fernando Muslera | 31 | Galatasaray |
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| 4 | Guillermo Varela | 25 | Peñarol |
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| 2 | José María Giménez | 23 | Atlético Madrid |
89'
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| 3 | Diego Godín | 32 | Atlético Madrid |
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| 22 | Martín Cáceres | 31 | Lazio |
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| 8 | Nahitan Nández | 22 | Boca Juniors |
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Out: 58' |
| 15 | Matías Vecino | 26 | Internazionale |
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Out: 87' |
| 6 | Rodrigo Bentancur | 20 | Juventus |
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| 10 | Giorgian De Arrascaeta | 24 | Cruzeiro |
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Out: 59' |
| 9 | Luis Suárez | 31 | Barcelona |
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| 21 | Edinson Cavani | 31 | PSG |
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| 5 | Carlos Sánchez | 33 | Monterrey |
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89'
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In: 58' |
| 7 | Cristian Rodríguez | 32 | Peñarol |
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In: 59' |
| 14 | Lucas Torreira | 22 | Sampdoria |
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In: 87' |
| Coach | Óscar Tabárez | 71 |
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