Starting XI with clubs
licensed under CC BY-NC 4.0
| No | Name | Age | Club | Goal | Assist | Card | Sub. |
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| 1 | Fernando Muslera | 33 | Galatasaray |
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| 4 | Giovanni González | 24 | Peñarol |
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70'
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| 2 | José María Giménez | 24 | Atlético Madrid |
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| 3 | Diego Godín | 33 | Atlético Madrid |
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| 22 | Martín Cáceres | 32 | Juventus |
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| 15 | Federico Valverde | 20 | Real Madrid |
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Out: 90' |
| 6 | Rodrigo Bentancur | 21 | Juventus |
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| 10 | Giorgian De Arrascaeta | 25 | Flamengo |
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Out: 76' |
| 7 | Nicolás Lodeiro | 30 | Seattle Sounders |
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Out: 46' |
| 21 | Edinson Cavani | 32 | PSG |
82'
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| 9 | Luis Suárez | 32 | Barcelona |
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| 8 | Nahitan Nández | 23 | Boca Juniors |
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In: 46' |
| 20 | Jonathan Rodríguez | 25 | Cruz Azul |
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82'
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In: 76' |
| 19 | Sebastián Coates | 28 | Sporting CP |
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In: 90' |
| Coach | Óscar Tabárez | 72 |
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