Starting XI with clubs
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| No | Name | Age | Club | Goal | Assist | Card | Sub. |
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| 1 | Fernando Muslera | 33 | Galatasaray |
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| 22 | Martín Cáceres | 32 | Fiorentina |
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| 19 | Sebastián Coates | 28 | Sporting CP |
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| 2 | José María Giménez | 24 | Atlético Madrid |
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| 3 | Matías Viña | 21 | Nacional |
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| 15 | Federico Valverde | 21 | Real Madrid |
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50'
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| 16 | Brian Rodríguez | 19 | Los Angeles |
50'
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Out: 61' |
| 6 | Rodrigo Bentancur | 22 | Juventus |
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Out: 82' |
| 5 | Matías Vecino | 28 | Internazionale |
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| 10 | Giorgian De Arrascaeta | 25 | Flamengo |
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| 20 | Jonathan Rodríguez | 26 | Cruz Azul |
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Out: 87' |
| 7 | Brian Lozano | 25 | Santos Laguna |
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In: 61' |
| 8 | Nahitan Nández | 23 | Cagliari |
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In: 82' |
| 18 | Maximiliano Gómez | 23 | Valencia |
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In: 87' |
| Coach | Óscar Tabárez | 72 |
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